Preskimmianine is primarily used in scientific research, particularly in the study of alkaloid biosynthesis and plant metabolism. It serves as an intermediate in the investigation of complex natural product pathways, especially those involving indole alkaloids. Due to its structural features, it is valuable in enzymatic studies to understand transformation steps in biosynthetic routes. It is not used in commercial or industrial applications and is not intended for pharmaceutical use. Its main role remains confined to laboratory settings for advancing knowledge in organic chemistry and phytochemistry.