This chemical is primarily used in the synthesis of complex molecules, particularly in the field of bioconjugation and click chemistry. Its trifluoroethyl group enhances stability and reactivity, making it valuable for attaching polyethylene glycol (PEG) chains to biomolecules like proteins, peptides, or antibodies. This process improves the solubility, stability, and bioavailability of these biomolecules, which is crucial in drug development and therapeutic applications.

Additionally, the propargyl group allows for efficient copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions, enabling precise and rapid conjugation of molecules in research and industrial settings. Its applications extend to the development of targeted drug delivery systems, diagnostic tools, and advanced materials in nanotechnology.