Used extensively in the field of bioconjugation, this chemical serves as a versatile linker for attaching various molecules, such as drugs, peptides, or proteins, to polyethylene glycol (PEG) chains. Its propargyl group enables click chemistry reactions, particularly with azides, facilitating the creation of stable triazole linkages. This property is highly valuable in drug delivery systems, where it enhances the solubility, stability, and bioavailability of therapeutic agents. Additionally, it is employed in the development of PEGylated biomaterials, which are crucial for improving the performance of medical devices and implants by reducing immune responses and preventing protein adsorption. Its application also extends to research in nanotechnology, where it aids in the synthesis of functionalized nanoparticles for targeted delivery and imaging purposes.