Sulfo dbco-peg4-maleimide
95%
Reagent
Code: #110249
CAS Number
2055198-07-5
blur_circular Chemical Specifications
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Molecular Information
Weight
296.38 g/mol
Formula
C₃₉H₄₇N₅O₁₃S
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Registry Numbers
MDL Number
MFCD30458040
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Storage & Handling
Storage
2-8°C, sealed, dry
description Product Description
Used in bioconjugation and labeling applications, particularly in click chemistry reactions. It serves as a linker for attaching biomolecules like proteins, peptides, or antibodies to other entities, such as fluorescent dyes or drug molecules. The maleimide group reacts selectively with thiol groups, while the DBCO (dibenzocyclooctyne) enables strain-promoted azide-alkyne cycloaddition (SPAAC) for efficient conjugation without the need for catalysts. This makes it valuable in drug delivery systems, diagnostic assays, and research tools for studying molecular interactions. Its PEG4 spacer enhances solubility and reduces steric hindrance, improving reaction efficiency.
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Sulfo dbco-peg4-maleimide
Used in bioconjugation and labeling applications, particularly in click chemistry reactions. It serves as a linker for attaching biomolecules like proteins, peptides, or antibodies to other entities, such as fluorescent dyes or drug molecules. The maleimide group reacts selectively with thiol groups, while the DBCO (dibenzocyclooctyne) enables strain-promoted azide-alkyne cycloaddition (SPAAC) for efficient conjugation without the need for catalysts. This makes it valuable in drug delivery systems, diagnostic assays, and research tools for studying molecular interactions. Its PEG4 spacer enhances solubility and reduces steric hindrance, improving reaction efficiency.
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