Dbco-Amine TFA is widely used in bioorthogonal chemistry for click chemistry reactions, particularly in the modification of biomolecules. It is highly effective in labeling proteins, peptides, and antibodies due to its ability to form stable triazole linkages with azide-containing compounds. This makes it a valuable tool in drug discovery, bioconjugation, and targeted drug delivery systems. Additionally, it is utilized in the development of fluorescent probes and imaging agents for studying biological processes in live cells. Its water solubility and reactivity under mild conditions further enhance its application in biotechnological and pharmaceutical research.