DBCO-PEG2-amine is widely used in bioconjugation and click chemistry applications due to its unique reactivity and water solubility. The DBCO (dibenzocyclooctyne) group enables strain-promoted azide-alkyne cycloaddition (SPAAC) reactions, allowing for efficient and selective coupling with azide-containing molecules without the need for catalysts. This makes it particularly valuable in labeling biomolecules, such as proteins, peptides, and antibodies, for imaging, diagnostics, and drug delivery systems. The PEG (polyethylene glycol) spacer enhances solubility and reduces steric hindrance, improving the efficiency of conjugation reactions. Additionally, the amine group provides a reactive site for further functionalization, enabling the attachment of various targeting ligands or fluorescent dyes. This compound is especially useful in the development of bioconjugates for targeted cancer therapies, where precise delivery of therapeutic agents is critical. Its versatility and biocompatibility also make it a key component in the design of advanced materials for biomedical research and nanotechnology applications.