DBCO-PEG2-NH-Boc is widely used in bioconjugation and click chemistry applications due to its unique properties. The DBCO (dibenzocyclooctyne) group enables strain-promoted azide-alkyne cycloaddition (SPAAC), a reaction that is highly efficient and does not require a catalyst. This makes it ideal for labeling biomolecules, such as proteins, peptides, and antibodies, in biological research and drug development. The PEG2 (polyethylene glycol) spacer enhances solubility and reduces steric hindrance, improving the efficiency of conjugation. The NH-Boc (amine protected with tert-butyloxycarbonyl) group allows for further functionalization after deprotection, making it versatile for synthesizing complex molecular structures. It is particularly useful in targeted drug delivery systems, diagnostic imaging, and the development of bioconjugates for therapeutic applications.