F-Amidine trifluoroacetate salt is widely used in organic synthesis, particularly in the preparation of amidine derivatives. It serves as a key intermediate in the development of pharmaceuticals, especially in the synthesis of compounds with potential antiviral, antibacterial, and anti-inflammatory properties. The compound is also utilized in peptide chemistry for modifying amino acids or peptides to enhance their biological activity or stability. Additionally, it finds application in material science for creating functionalized polymers or coatings with specific chemical properties. Its reactivity and stability make it a valuable reagent in various research and industrial processes.