Ethyl N-Boc-oxamidate is primarily used in organic synthesis as a protecting group for amines. It is particularly valuable in peptide chemistry, where it helps safeguard amino groups during complex reactions, ensuring selective modification of other functional groups. This compound is also employed in the preparation of intermediates for pharmaceuticals, enabling the synthesis of complex molecules with high precision. Additionally, it finds use in the development of bioactive compounds, where its stability and ease of removal make it a preferred choice for protecting sensitive amine functionalities.