N-Fmoc-O-(2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-α-D-galactopyranosyl)-L-threonine
≥98%
- Product Code: 103844
Alias:
Fmoc-Thr[GalNAc(Ac)3-α-D]-OH
CAS:
116783-35-8
| Molecular Weight: | 670.66 g./mol | Molecular Formula: | C₃₃H₃₈N₂O₁₃ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD00171374 | |
| Melting Point: | 178-183 °C | Boiling Point: | |
| Density: | Storage Condition: | −20°C |
Product Description:
This chemical is primarily used in the synthesis of glycopeptides, which are important in biochemical and pharmaceutical research. It serves as a protected glycosylated amino acid, enabling the construction of complex glycopeptide structures. The Fmoc group provides protection for the amino group during solid-phase peptide synthesis, while the acetyl groups protect the hydroxyl groups on the sugar moiety. This allows for selective deprotection and further functionalization. Its application is crucial in studying protein glycosylation, a process vital for understanding cell signaling, immune response, and disease mechanisms. Additionally, it is utilized in the development of glycopeptide-based therapeutics, including vaccines and cancer treatments.
Product Specification:
| Test | Specification |
|---|---|
| Appearance | White To Yellow And Faint Beige To Beige And Faint Brown To Brown Powder Or Crystals |
| Purity (%) | 98 |
| Proton NMR Spectra | Conforms To Structure |
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.005 | 10-20 days | $123.76 |
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| 0.025 | 10-20 days | $497.52 |
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N-Fmoc-O-(2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-α-D-galactopyranosyl)-L-threonine
This chemical is primarily used in the synthesis of glycopeptides, which are important in biochemical and pharmaceutical research. It serves as a protected glycosylated amino acid, enabling the construction of complex glycopeptide structures. The Fmoc group provides protection for the amino group during solid-phase peptide synthesis, while the acetyl groups protect the hydroxyl groups on the sugar moiety. This allows for selective deprotection and further functionalization. Its application is crucial in studying protein glycosylation, a process vital for understanding cell signaling, immune response, and disease mechanisms. Additionally, it is utilized in the development of glycopeptide-based therapeutics, including vaccines and cancer treatments.
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