Z-Asp(OtBu)-OH

98%

  • Product Code: 105665
  Alias:    CBZ-L-aspartic acid 4-tert-butyl ester
  CAS:    5545-52-8
Molecular Weight: 323.34 g./mol Molecular Formula: C₁₆H₂₁NO₆
EC Number: 226-912-0 MDL Number: MFCD00042857
Melting Point: Boiling Point:
Density: Storage Condition: Room temperature, dry, sealed
Product Description: Z-Asp(OtBu)-OH is widely used in peptide synthesis as a protected form of aspartic acid. Its tert-butyl ester group provides stability during the coupling reactions, ensuring the aspartic acid residue remains intact while other amino acids are added to the peptide chain. This compound is particularly valuable in solid-phase peptide synthesis (SPPS), where selective deprotection is required to build complex peptides. It is also employed in the synthesis of peptide-based drugs, where precise control over the sequence and structure is critical. Additionally, Z-Asp(OtBu)-OH is utilized in research for developing bioactive peptides, enzyme inhibitors, and other therapeutic agents, owing to its ability to maintain the integrity of the aspartic acid side chain during chemical processes.
Product Specification:
Test Specification
Carbon By Elemental Analysis 58-59.9
Oxygen By Elemental Analysis 28.7-29.9
Purity (GC) 97.5-100
Specific Rotation 24-35
Appearance White To Light Yellow Powder
Infrared Spectrometry Conforms To Structure
Sizes / Availability / Pricing:
Size (g) Availability Price Quantity
1.000 10-20 days $15.03
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-
5.000 10-20 days $38.51
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25.000 10-20 days $136.20
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-
100.000 10-20 days $498.76
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Z-Asp(OtBu)-OH
Z-Asp(OtBu)-OH is widely used in peptide synthesis as a protected form of aspartic acid. Its tert-butyl ester group provides stability during the coupling reactions, ensuring the aspartic acid residue remains intact while other amino acids are added to the peptide chain. This compound is particularly valuable in solid-phase peptide synthesis (SPPS), where selective deprotection is required to build complex peptides. It is also employed in the synthesis of peptide-based drugs, where precise control over the sequence and structure is critical. Additionally, Z-Asp(OtBu)-OH is utilized in research for developing bioactive peptides, enzyme inhibitors, and other therapeutic agents, owing to its ability to maintain the integrity of the aspartic acid side chain during chemical processes.
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