Boc-(R)-4-[4-(trifluoromethyl)benzyl]-L-proline
≥98%(HPLC)
- Product Code: 156384
CAS:
957311-17-0
| Molecular Weight: | 373.37 g./mol | Molecular Formula: | C₁₈H₂₂F₃NO₄ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD06659430 | |
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | 2-8°C, Inert Gas |
Product Description:
Used in pharmaceutical synthesis as a chiral building block for developing protease inhibitors and other bioactive molecules. The Boc-protected proline scaffold with a trifluoromethylbenzyl substituent enhances metabolic stability and binding selectivity in drug candidates. Commonly employed in the preparation of peptidomimetics, particularly in research targeting enzymes where stereochemistry and fluorination improve potency. The (R)-configuration at the 4-position allows access to specific conformational constraints important for receptor interaction. Widely applied in medicinal chemistry for structure-activity relationship (SAR) studies and optimization of lead compounds.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 0.100 G | 10-20 days | ฿11,390.00 |
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| 0.500 G | 10-20 days | ฿44,080.00 |
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Boc-(R)-4-[4-(trifluoromethyl)benzyl]-L-proline
Used in pharmaceutical synthesis as a chiral building block for developing protease inhibitors and other bioactive molecules. The Boc-protected proline scaffold with a trifluoromethylbenzyl substituent enhances metabolic stability and binding selectivity in drug candidates. Commonly employed in the preparation of peptidomimetics, particularly in research targeting enzymes where stereochemistry and fluorination improve potency. The (R)-configuration at the 4-position allows access to specific conformational constraints important for receptor interaction. Widely applied in medicinal chemistry for structure-activity relationship (SAR) studies and optimization of lead compounds.
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