(R)-2-((tert-Butoxycarbonyl)amino)-3-(4-(tert-butyl)phenyl)propanoic acid
95%
- Product Code: 231865
CAS:
250611-12-2
| Molecular Weight: | 321.41 g./mol | Molecular Formula: | C₁₈H₂₇NO₄ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD02094579 | |
| Melting Point: | Boiling Point: | 461.413 °C at 760 mmHg | |
| Density: | Storage Condition: | 2-8°C, sealed, dry |
Product Description:
Widely used in peptide synthesis as a chiral building block, this compound serves as a protected amino acid derivative, particularly in the preparation of complex bioactive molecules. Its tert-butoxycarbonyl (Boc) group allows for selective protection of the amine functionality, enabling controlled stepwise coupling in solid-phase or solution-phase peptide assembly. The presence of the bulky 4-(tert-butyl)phenyl side chain enhances stereochemical stability and influences conformational behavior in the resulting peptides. It is especially valuable in the synthesis of enzyme inhibitors, receptor ligands, and pharmaceutical intermediates where stereoselectivity and side chain specificity are critical. The carboxylic acid group can be readily activated for amide bond formation, making it compatible with standard coupling reagents and automated synthesis protocols.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 0.250 | 10-20 days | ฿4,110.00 |
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| 1.000 | 10-20 days | ฿11,080.00 |
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| 5.000 | 10-20 days | ฿44,900.00 |
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(R)-2-((tert-Butoxycarbonyl)amino)-3-(4-(tert-butyl)phenyl)propanoic acid
Widely used in peptide synthesis as a chiral building block, this compound serves as a protected amino acid derivative, particularly in the preparation of complex bioactive molecules. Its tert-butoxycarbonyl (Boc) group allows for selective protection of the amine functionality, enabling controlled stepwise coupling in solid-phase or solution-phase peptide assembly. The presence of the bulky 4-(tert-butyl)phenyl side chain enhances stereochemical stability and influences conformational behavior in the resulting peptides. It is especially valuable in the synthesis of enzyme inhibitors, receptor ligands, and pharmaceutical intermediates where stereoselectivity and side chain specificity are critical. The carboxylic acid group can be readily activated for amide bond formation, making it compatible with standard coupling reagents and automated synthesis protocols.
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