Used as a key building block in medicinal chemistry, particularly in the development of bioactive molecules and pharmaceuticals. Its rigid bicyclic structure enhances metabolic stability and improves binding selectivity, making it valuable in designing drugs targeting central nervous system disorders and other therapeutic areas. Commonly employed in fragment-based drug discovery to replace phenyl or other planar groups, improving pharmacokinetic properties such as solubility and membrane permeability. Also utilized in the synthesis of novel amide and urea derivatives for structure-activity relationship studies.