This compound is widely used in bioconjugation and chemical biology research. It serves as a linker for attaching aminooxy-functionalized molecules to carbonyl-containing compounds, enabling the formation of stable oxime bonds. Its PEG4 spacer provides flexibility and solubility, making it suitable for modifying peptides, proteins, and other biomolecules. It is particularly useful in drug delivery systems, where it helps create targeted conjugates with improved pharmacokinetic properties. Additionally, it is employed in the development of antibody-drug conjugates (ADCs) and other therapeutic bioconjugates, enhancing their stability and efficacy. Its application also extends to surface modification and material science, where it facilitates the functionalization of nanoparticles and other substrates.