t-Boc-Aminooxy-PEG8-alcohol is widely used in bioconjugation and chemical biology for attaching biomolecules to various substrates. Its PEG (polyethylene glycol) spacer enhances solubility and reduces steric hindrance, making it ideal for linking proteins, peptides, or other molecules. The aminooxy group allows for efficient conjugation with aldehydes or ketones, enabling the formation of stable oxime bonds. This chemical is particularly valuable in the development of antibody-drug conjugates (ADCs), where it facilitates the attachment of therapeutic agents to antibodies. Additionally, it is employed in surface modification of nanoparticles or biomaterials to improve biocompatibility and targeting efficiency. Its t-Boc protecting group ensures selective deprotection, enabling controlled and site-specific reactions in complex synthetic processes.