PEPA is widely used in the field of neuroscience research as a potent and selective agonist for AMPA receptors. These receptors play a crucial role in fast synaptic transmission in the central nervous system, making PEPA a valuable tool for studying excitatory neurotransmission and synaptic plasticity. Its application extends to investigating mechanisms underlying learning, memory, and neurological disorders such as epilepsy and neurodegenerative diseases. Additionally, PEPA is utilized in pharmacological studies to explore the effects of modulating AMPA receptor activity, aiding in the development of potential therapeutic agents for cognitive and neurological conditions.