AMPA/kainate antagonist-1 is primarily used in neuroscience research to study the role of glutamate receptors in the central nervous system. It acts as an antagonist to AMPA and kainate receptors, which are involved in excitatory synaptic transmission. By blocking these receptors, this compound helps researchers investigate conditions such as epilepsy, neurodegenerative diseases, and stroke, where excessive glutamate activity can lead to neuronal damage. It is also utilized in preclinical studies to explore potential therapeutic strategies for managing these disorders. Additionally, it aids in understanding the mechanisms of synaptic plasticity, learning, and memory, which are influenced by glutamate receptor activity.