Boc-Arg(Tos)-OH
98%
Reagent
Code: #126682
Alias
N-tert-butoxycarbonyl-N'-toluenesulfonyl-L-arginine ;N-tert-butoxycarbonyl-N'-toluenesulfonyl-L-arginine
CAS Number
13836-37-8
science Other reagents with same CAS 13836-37-8
blur_circular Chemical Specifications
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Molecular Information
Weight
428.51 g/mol
Formula
C₁₈H₂₈N₄O₆S
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Registry Numbers
EC Number
237-549-2
MDL Number
MFCD00065557
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Physical Properties
Melting Point
~90 °C (dec.)
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Storage & Handling
Storage
room temperature
description Product Description
Boc-Arg(Tos)-OH is widely used in peptide synthesis as a protected form of arginine. The tert-butyloxycarbonyl (Boc) group safeguards the amino group, while the tosyl (Tos) group protects the guanidine side chain, preventing unwanted reactions during the peptide chain assembly. This compound is particularly valuable in solid-phase peptide synthesis (SPPS), where selective deprotection allows for the stepwise construction of peptides. It ensures high purity and yield by minimizing side reactions. Additionally, it is employed in the synthesis of bioactive peptides, pharmaceuticals, and research compounds where arginine plays a critical role. Its stability and ease of deprotection make it a preferred choice in organic and medicinal chemistry.
format_list_bulleted Product Specification
| Test Parameter | Specification |
|---|---|
| Appearance | White To Almost White Powder To Crystal |
| Purity (%) | 97.5-100% |
| Specific Rotation [α]20/D (C=4, DMF) | -5.0 to -3.0 |
| Infrared Spectrum | Conforms To Structure |