5-(4-Fluorophenyl)-1H-tetrazole
97%
Reagent
Code: #188339
CAS Number
50907-21-6
science Other reagents with same CAS 50907-21-6
blur_circular Chemical Specifications
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Molecular Information
Weight
164.14 g/mol
Formula
C₇H₅FN₄
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Registry Numbers
MDL Number
MFCD00478201
thermostat
Physical Properties
Melting Point
210-212 °C
Boiling Point
322 °C at 760 mmHg
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Storage & Handling
Density
1.403 g/cm3
Storage
2-8°C
description Product Description
Used as a key intermediate in the synthesis of angiotensin II receptor antagonists, particularly in the production of antihypertensive drugs like losartan and other sartan-class medications. Its tetrazole ring serves as a bioisostere for the carboxylic acid group, enhancing metabolic stability and improving oral bioavailability. Also employed in coordination chemistry as a ligand for metal ions in catalytic systems. Finds use in research for developing new pharmaceuticals and functional materials due to its polarity and hydrogen bonding capability.