N-Benzoyl-(2R, 3S)-3-phenylisoserine, taxol side chain
10mM in DMSO
Reagent
Code: #216282
CAS Number
132201-33-3
science Other reagents with same CAS 132201-33-3
blur_circular Chemical Specifications
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Molecular Information
Weight
285.29 g/mol
Formula
C₁₆H₁₅NO₄
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Registry Numbers
MDL Number
MFCD00274633
thermostat
Physical Properties
Melting Point
169-172 °C
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Storage & Handling
Storage
-20°C
description Product Description
Used as a key intermediate in the synthesis of paclitaxel (Taxol), a potent anticancer drug. It plays a critical role in constructing the ester side chain essential for Taxol’s biological activity. This compound enables efficient semisynthesis of Taxol and its analogs, supporting large-scale production for chemotherapy treatments, particularly in ovarian, breast, and lung cancers. Its stereochemistry is crucial for maintaining the drug’s ability to stabilize microtubules and inhibit cell division.