N-tert-Butylmaleimide
97%
Reagent
Code: #217120
CAS Number
4144-22-3
blur_circular Chemical Specifications
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Molecular Information
Weight
153.18 g/mol
Formula
C₈H₁₁NO₂
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Registry Numbers
MDL Number
MFCD00191885
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Physical Properties
Boiling Point
189°C (Lit.)
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Storage & Handling
Storage
Room temperature, seal, dry
description Product Description
Used as a protecting group in organic synthesis, particularly for amines and amino acids, due to its ability to selectively react with primary amines. It is widely employed in peptide chemistry to prevent unwanted side reactions during multi-step syntheses. Its bulky tert-butyl group enhances steric hindrance, improving selectivity. Also utilized in the preparation of functionalized polymers and as a building block in medicinal chemistry for designing bioactive molecules. Common in research settings for modifying proteins and studying molecular interactions.
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N-tert-Butylmaleimide
Used as a protecting group in organic synthesis, particularly for amines and amino acids, due to its ability to selectively react with primary amines. It is widely employed in peptide chemistry to prevent unwanted side reactions during multi-step syntheses. Its bulky tert-butyl group enhances steric hindrance, improving selectivity. Also utilized in the preparation of functionalized polymers and as a building block in medicinal chemistry for designing bioactive molecules. Common in research settings for modifying proteins and studying molecular interactions.
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