(S)-(-)-2-Methyl-CBS-oxazaborolidine
98%
Reagent
Code: #234309
Alias
(S)-5,5-biphenyl-2-methyl-3,4-propanol-1,3,2-oxazoleborane(S)-2-methyl-CBS-oxaboridine(S)-2-methyl-CBS-oxazoleboridine(S)-2-methyl-CBS-oxazoleborane
CAS Number
112022-81-8
science Other reagents with same CAS 112022-81-8
blur_circular Chemical Specifications
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Molecular Information
Weight
277.17 g/mol
Formula
C₁₈H₂₀BNO
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Registry Numbers
MDL Number
MFCD00078439
thermostat
Physical Properties
Melting Point
115-117°C
Boiling Point
111 °C
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Storage & Handling
Density
0.93 g/mL at 20 °C(lit.)
Storage
Room temperature
description Product Description
Used as a chiral catalyst in asymmetric synthesis, particularly in the reduction of prochiral ketones to produce enantiomerically enriched secondary alcohols. It is highly effective in borane-mediated reductions, offering high selectivity and yield. Commonly applied in pharmaceutical synthesis where precise stereochemistry is critical. Its structure allows for efficient control of the reaction’s stereochemical outcome, making it valuable in the preparation of chiral intermediates for drugs and fine chemicals.
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