Solanesol, derived from tobacco plants, is primarily used in the pharmaceutical industry as a key intermediate in the synthesis of coenzyme Q10 (ubiquinone) and vitamin K analogs, which are vital for cellular energy production and blood clotting, respectively. It exhibits strong antioxidant properties, supporting cardiovascular health and protecting against oxidative stress. Due to its long carbon chain and lipophilic nature, solanesol serves as a skin-conditioning agent in cosmetic formulations, enhancing moisture retention, improving skin texture, delaying wrinkles, and shielding from UV damage and pollution. Additionally, ongoing research investigates its immunomodulatory, anti-inflammatory, antiviral, and anti-cancer effects, including potential inhibition of abnormal cell growth, making it a candidate for vaccine adjuvants, topical therapeutics, and supplements for heart and immune health. Its natural extraction from tobacco waste underscores its value in sustainable, high-value applications.