Used in catalysts for organic reactions and in the production of special glasses and ceramics due to its thermal stability. Employed in electronics for making capacitors and magnetic materials, including high-strength neodymium-iron-boron magnets doped with samarium oxide to enhance resistance to demagnetization from magnetic fields or high temperatures.

Also utilized in neutron absorption in nuclear reactors and in phosphors for lighting and display technologies.

Shows promise in medical applications such as cancer treatment through radiation therapy enhancement using samarium isotopes.