Used as a chiral auxiliary or intermediate in asymmetric synthesis, particularly in the development of pharmaceuticals. Its rigid, bicyclic structure with defined stereochemistry enables high stereoselectivity in reactions such as alkylations, aldol additions, and cyclizations. Commonly employed in the synthesis of bioactive molecules where control of stereochemistry is critical, including protease inhibitors and other enzyme-targeted drugs. The sulfonamide group enhances stability and can participate in hydrogen bonding, aiding in substrate control during transformations.