Trimethyl(propargyl)silane
97%(total of isomer), ≤20% trimethylallenylsilane (in equilibrium), 500 ppm BHT as stabilizer
science Other reagents with same CAS 13361-64-3
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description Product Description
Used as a versatile reagent in organic synthesis, particularly in cross-coupling reactions (e.g., Sonogashira coupling) and silylation processes. Its propargyl group enables participation in metal-catalyzed reactions and click chemistry (e.g., CuAAC with azides), making it valuable for constructing carbon-carbon bonds in pharmaceutical and agrochemical intermediates. The trimethylsilyl group facilitates regioselective functionalization of the propargyl moiety and can be selectively cleaved under mild conditions, allowing for controlled reaction sequences. Commonly employed in the synthesis of complex molecules where functional group compatibility and regioselectivity are important. Also finds use in materials science for modifying surfaces and preparing silicon-based polymers with tailored properties.
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