Bithionol is primarily used as an antiparasitic agent, particularly effective against liver flukes in livestock and other helminthic infections. It has been used in veterinary medicine to treat fascioliasis in sheep, cattle, and goats. Though its use in humans is limited, it has shown activity against certain tapeworms and flukes. Additionally, bithionol has been investigated for its potential antiviral properties, especially against some enveloped viruses, due to its ability to disrupt membrane integrity. It has also been used in topical formulations for skin conditions in some regions, leveraging its antimicrobial and anti-inflammatory effects. However, its systemic use is restricted due to toxicity concerns.