Used topically as an anti-inflammatory agent, primarily in the treatment of skin conditions such as eczema, dermatitis, and other inflammatory skin disorders. It helps reduce redness, swelling, and itching associated with these conditions. Bufexamac is often found in prescription creams and ointments, particularly in some European and Asian countries. Due to concerns about potential skin sensitization and carcinogenic impurities, its use has been restricted or discontinued in certain regions.