Trifluoroacetic acid (TFA)
Reagent grade, 99.0%
- Product Code: 239654
Alias:
Trifluoroacetic acid (TFA); trifluoroacetic acid
CAS:
76-05-1
| Molecular Weight: | 114.02 g./mol | Molecular Formula: | C₂HO₂F₃ |
|---|---|---|---|
| EC Number: | 200-929-3 | MDL Number: | MFCD00004169 |
| Melting Point: | -15 °C | Boiling Point: | 72.4 °C(lit.) |
| Density: | 1.489 g/mL at 20 °C(lit.) | Storage Condition: | Room temperature |
Product Description:
Widely used in peptide synthesis as a reagent for deprotection and cleavage from solid supports due to its strong acidity and ability to volatilize easily, allowing for simple removal. Commonly employed in high-performance liquid chromatography (HPLC) as an ion-pairing agent to improve separation of polar and basic compounds. Serves as a catalyst and solvent in organic reactions, including esterifications and Friedel-Crafts acylations, where its non-nucleophilic nature is advantageous. Also utilized in the production of pharmaceuticals, agrochemicals, and specialty fluorinated compounds thanks to its stability and reactivity.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 25g | 10-20 days | ฿500.00 |
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| 100ml | 10-20 days | ฿1,050.00 |
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| 500g | 10-20 days | ฿3,200.00 |
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| 2.5L | 10-20 days | ฿15,980.00 |
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| 12X500ml | 10-20 days | ฿43,710.00 |
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| 25ml | 10-20 days | ฿520.00 |
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| 500ml | 10-20 days | ฿3,680.00 |
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| 100g | 10-20 days | ฿720.00 |
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Trifluoroacetic acid (TFA)
Widely used in peptide synthesis as a reagent for deprotection and cleavage from solid supports due to its strong acidity and ability to volatilize easily, allowing for simple removal. Commonly employed in high-performance liquid chromatography (HPLC) as an ion-pairing agent to improve separation of polar and basic compounds. Serves as a catalyst and solvent in organic reactions, including esterifications and Friedel-Crafts acylations, where its non-nucleophilic nature is advantageous. Also utilized in the production of pharmaceuticals, agrochemicals, and specialty fluorinated compounds thanks to its stability and reactivity.
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