Trifluoroacetic acid (TFA)
99.9%
- Product Code: 239656
Alias:
Trifluoroacetic acid (TFA); trifluoroacetic acid
CAS:
76-05-1
| Molecular Weight: | 114.02 g./mol | Molecular Formula: | C₂HO₂F₃ |
|---|---|---|---|
| EC Number: | 200-929-3 | MDL Number: | MFCD00004169 |
| Melting Point: | -15 °C | Boiling Point: | 72.4 °C(lit.) |
| Density: | 1.489 g/mL at 20 °C(lit.) | Storage Condition: | Room temperature |
Product Description:
Trifluoroacetic acid is widely used as a reagent and solvent in organic synthesis. It is particularly effective in deprotection reactions, such as removing tert-butyloxycarbonyl (Boc) and tert-butyl ester protecting groups in peptide and nucleotide synthesis. Due to its strong acidity and volatility, it can be easily removed after reaction completion, making it ideal for purification processes.
It serves as a catalyst in esterifications, acylations, and polymerizations. In chromatography, especially HPLC, TFA is commonly used as an ion-pairing agent in mobile phases to improve the separation of polar and basic compounds.
TFA is also employed in the production of pharmaceuticals, agrochemicals, and liquid crystals, where it helps in the synthesis of fluorinated compounds that exhibit enhanced stability and bioavailability. Its ability to stabilize reactive intermediates makes it valuable in the preparation of specialty chemicals and fluorinated building blocks.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 25ml | 10-20 days | ฿590.00 |
+
-
|
| 100ml | 10-20 days | ฿1,660.00 |
+
-
|
| 250ml | 10-20 days | ฿3,090.00 |
+
-
|
| 500ml | 10-20 days | ฿5,980.00 |
+
-
|
| 2.5L | 10-20 days | ฿25,180.00 |
+
-
|
| 12X500ml | 10-20 days | ฿71,500.00 |
+
-
|
Trifluoroacetic acid (TFA)
Trifluoroacetic acid is widely used as a reagent and solvent in organic synthesis. It is particularly effective in deprotection reactions, such as removing tert-butyloxycarbonyl (Boc) and tert-butyl ester protecting groups in peptide and nucleotide synthesis. Due to its strong acidity and volatility, it can be easily removed after reaction completion, making it ideal for purification processes.
It serves as a catalyst in esterifications, acylations, and polymerizations. In chromatography, especially HPLC, TFA is commonly used as an ion-pairing agent in mobile phases to improve the separation of polar and basic compounds.
TFA is also employed in the production of pharmaceuticals, agrochemicals, and liquid crystals, where it helps in the synthesis of fluorinated compounds that exhibit enhanced stability and bioavailability. Its ability to stabilize reactive intermediates makes it valuable in the preparation of specialty chemicals and fluorinated building blocks.
| Mechanism | - |
| Appearance | - |
| Longevity | - |
| Strength | - |
| Storage | - |
| Shelf Life | - |
| Allergen(s) | - |
| Dosage (Range) | - |
| Recommended Dosage | - |
| Dosage (Per Day) | - |
| Recommended Dosage (Per Day) | - |
| Mix Method | - |
| Heat Resistance | - |
| Stable in pH range | - |
| Solubility | - |
| Product Types | - |
| INCI | - |
Purchase History for
Loading purchase history...
Cart
No products
Subtotal:
฿0.00
฿0.00
Total :