Trifluoroacetic acid (TFA)
for HPLC, ≥99.5%
- Product Code: 93269
Alias:
Trifluoroacetic acid
CAS:
76-05-1
| Molecular Weight: | 114.02 g./mol | Molecular Formula: | C₂HO₂F₃ |
|---|---|---|---|
| EC Number: | 200-929-3 | MDL Number: | MFCD00004169 |
| Melting Point: | -15 °C | Boiling Point: | 72.4 °C(lit.) |
| Density: | 1.489 g/mL at 20 °C(lit.) | Storage Condition: | room temperature |
Product Description:
Trifluoroacetic acid (TFA) is widely used in organic synthesis as a strong acid catalyst for various reactions, including esterifications, acylations, and deprotections. It is particularly valued in peptide synthesis for removing protecting groups like t-butyl and benzyl, ensuring high yields and purity. In the pharmaceutical industry, TFA is employed in the purification and analysis of compounds, often as a mobile phase additive in HPLC to improve separation efficiency. Additionally, TFA serves as a solvent for highly polar substances and is utilized in the production of polymers, dyes, and agricultural chemicals. Its strong acidity and volatility make it a versatile reagent in both laboratory and industrial settings.
Product Specification:
| Test | Specification |
|---|---|
| UV ABSORPTION 260NM | 0-0.9 |
| 270NM | 0-0.1 |
| 280NM | 0-0.05 |
| 290NM | 0.04 |
| 300NM | 0-0.03 |
| 320NM | 0-0.025 |
| WATER BY KARL FISCHER | 0 % 0.05 % |
| APPEARANCE | Colorless liquid |
| REFRACTIVE INDEXN20D | 1.2830-1.2870 |
| PURITY | 99.5-100 |
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 25.000 | 10-20 days | Ft6,679.95 |
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| 100.000 | 10-20 days | Ft18,100.50 |
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| 500.000 | 10-20 days | Ft64,429.17 |
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| 2500.000 | 10-20 days | Ft232,720.73 |
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Trifluoroacetic acid (TFA)
Trifluoroacetic acid (TFA) is widely used in organic synthesis as a strong acid catalyst for various reactions, including esterifications, acylations, and deprotections. It is particularly valued in peptide synthesis for removing protecting groups like t-butyl and benzyl, ensuring high yields and purity. In the pharmaceutical industry, TFA is employed in the purification and analysis of compounds, often as a mobile phase additive in HPLC to improve separation efficiency. Additionally, TFA serves as a solvent for highly polar substances and is utilized in the production of polymers, dyes, and agricultural chemicals. Its strong acidity and volatility make it a versatile reagent in both laboratory and industrial settings.
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