Topilutamide is primarily used in medical research and clinical applications related to androgen-dependent conditions. It functions as an antiandrogen, making it valuable in the treatment of prostate cancer by inhibiting the effects of androgens, which can promote tumor growth. Additionally, it has been explored for managing conditions like hirsutism and acne, where androgen activity plays a significant role. Its ability to block androgen receptors makes it a potential candidate for addressing hormonal imbalances and related disorders.