2-(2-Butyl-4-methyl-6-oxo-1-((2'-(1-trityl-1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-1,6-dihydropyrimidin-5-yl)-N,N-dimethylacetamide
95%
Reagent
Code: #140954
CAS Number
503155-67-7
blur_circular Chemical Specifications
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Molecular Information
Weight
727.9 g/mol
Formula
C₄₆H₄₅N₇O₂
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Registry Numbers
MDL Number
MFCD28399040
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Physical Properties
Boiling Point
882.1±75.0 °C(Predicted)
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Storage & Handling
Density
1.17 g/cm3
Storage
2-8°C, Inert Gas
description Product Description
Used in the synthesis of angiotensin II receptor antagonists, particularly in the development of sartan-class antihypertensive drugs. The compound acts as a key intermediate due to its functionalized pyrimidine core and tetrazole moiety, both of which are critical for binding to the angiotensin II receptor. Its structure allows for further chemical modifications to enhance pharmacokinetic properties such as bioavailability and metabolic stability. Commonly employed in pharmaceutical research for optimizing drug candidates targeting hypertension and related cardiovascular conditions.
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