2-Benzyl-2H-tetrazole-5-carboxylic acid
98%
Reagent
Code: #141246
CAS Number
55408-13-4
blur_circular Chemical Specifications
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Molecular Information
Weight
204.19 g/mol
Formula
C₉H₈N₄O₂
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Storage & Handling
Storage
2-8°C, Inert Gas
description Product Description
Used as a key intermediate in the synthesis of angiotensin II receptor antagonists, particularly in the production of sartan-class antihypertensive drugs such as candesartan and olmesartan. Its tetrazole ring mimics the carboxylic acid group in biological systems, enhancing binding affinity to the angiotensin II receptor. Also employed in medicinal chemistry for developing new bioactive molecules due to its metabolic stability and ability to improve pharmacokinetic properties. Additionally, it serves as a building block in click chemistry and coordination chemistry for designing metal-organic frameworks and catalysts.
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