2-Boc-4'-(Bromomethyl)biphenyl
95%
Reagent
Code: #145772
CAS Number
114772-40-6
blur_circular Chemical Specifications
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Molecular Information
Weight
347.25 g/mol
Formula
C₁₈H₁₉BrO₂
thermostat
Physical Properties
Boiling Point
437°C
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Storage & Handling
Storage
2-8°C
description Product Description
Used as a key intermediate in the synthesis of angiotensin II receptor antagonists, particularly in the preparation of losartan and related sartan-class antihypertensive drugs. The bromomethyl group allows for nucleophilic substitution reactions, enabling the introduction of heterocyclic moieties, while the Boc-protected biphenyl scaffold provides stability and selectivity during multi-step syntheses. Commonly employed in pharmaceutical research and development for constructing complex biaryl structures with high functional group tolerance.
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