O-(4-Biphenylylcarbonyl)Benzoic Acid
≥97%
Reagent
Code: #147095
CAS Number
42797-18-2
blur_circular Chemical Specifications
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Molecular Information
Weight
302.32 g/mol
Formula
C₂₀H₁₄O₃
thermostat
Physical Properties
Melting Point
225-227ºC
Boiling Point
225-227ºC
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Storage & Handling
Density
1.232g/cm3
Storage
Room temperature, dry
description Product Description
Used as a key intermediate in the synthesis of angiotensin II receptor antagonists, particularly in the production of antihypertensive drugs like valsartan and related pharmaceuticals. Its structure enables the formation of biaryl motifs common in sartan-class medications, which block the action of angiotensin II, helping to relax blood vessels and lower blood pressure. It is employed in multi-step organic syntheses where selective coupling and esterification reactions are required to build the active pharmaceutical ingredient. Commonly utilized in research and industrial settings for developing cardiovascular therapeutics.
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