5-(5-Bromothiophen-2-yl)-1H-tetrazole

≥98%

Reagent Code: #149540
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CAS Number 211943-12-3

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 231.07 g/mol
Formula C₅H₃BrN₄S
badge Registry Numbers
MDL Number MFCD01075734
thermostat Physical Properties
Boiling Point 157-158  °C
inventory_2 Storage & Handling
Density 1.087 g/mL at 25 °C
Storage 2-8°C

description Product Description

Used as a key intermediate in the synthesis of angiotensin II receptor antagonists, particularly in the production of sartan-class antihypertensive drugs such as valsartan and losartan. The tetrazole ring serves as a bioisostere for the carboxylic acid group, enhancing metabolic stability and improving oral bioavailability. Its brominated thiophene moiety allows for further functionalization via cross-coupling reactions, making it valuable in medicinal chemistry for building complex drug molecules. Also employed in the development of new heterocyclic compounds with potential biological activity, including antimicrobial and anti-inflammatory agents.

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Test Parameter Specification
Appearance White to Off-White to Light brown Solid
Purity (%) 98.0-100
Infrared Spectrum Conforms to Structure
NMR Conforms to Structure

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 250mg
10-20 days ฿2,890.00
inventory 1g
10-20 days ฿9,630.00
inventory 5g
10-20 days ฿43,780.00

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