5-(4-(tert-Butyl)phenyl)-2H-tetrazole
95%
Reagent
Code: #149968
CAS Number
126393-38-2
blur_circular Chemical Specifications
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Molecular Information
Weight
202.26 g/mol
Formula
C₁₁H₁₄N₄
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Registry Numbers
MDL Number
MFCD00673172
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Storage & Handling
Storage
2-8°C
description Product Description
Used as a key intermediate in the synthesis of angiotensin II receptor antagonists, particularly in the production of sartan-class antihypertensive drugs such as losartan and valsartan. Its tetrazole ring serves as a bioisostere for the carboxylic acid group, enhancing metabolic stability and improving pharmacokinetic properties. Commonly employed in pharmaceutical research and development for optimizing drug candidates targeting cardiovascular diseases. Also utilized in coordination chemistry as a ligand due to its nitrogen-rich structure, enabling complexation with metal ions for catalytic or material applications.
format_list_bulleted Product Specification
| Test Parameter | Specification |
|---|---|
| Appearance | solid |
| Purity (%) | 94.5-100% |
| Infrared Spectrum | Conforms to Structure |
| NMR | Conforms to Structure |
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