4'-(Bromomethyl)-[1, 1'-biphenyl]-2-carboxylic acid

95%

Reagent Code: #152021
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CAS Number 150766-86-2

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 291.14 g/mol
Formula C₁₄H₁₁BrO₂
badge Registry Numbers
MDL Number MFCD06208233
inventory_2 Storage & Handling
Storage 2-8°C, dry

description Product Description

Used as a key intermediate in the synthesis of angiotensin II receptor antagonists, such as valsartan and related sartan-class antihypertensive drugs. Its structure allows for the introduction of biphenyl motifs with functional handles that are essential for binding to the angiotensin receptor. The bromomethyl group serves as a reactive site for alkylation or nucleophilic substitution, enabling coupling with nitrogen-containing heterocycles in active pharmaceutical ingredients. Also employed in the preparation of specialty polymers and liquid crystals where controlled molecular architecture is required. Its carboxylic acid functionality allows for easy derivatization into esters, amides, or salts to fine-tune solubility and reactivity in multi-step organic syntheses.

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 100mg
10-20 days ฿5,060.00
inventory 250mg
10-20 days ฿6,860.00
inventory 1g
10-20 days ฿22,150.00

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