5-(5-Chloro-2-Thienyl)-1H-Tetrazole
≥95%
Reagent
Code: #163115
CAS Number
58884-89-2
blur_circular Chemical Specifications
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Molecular Information
Weight
186.62 g/mol
Formula
C₅H₃ClN₄S
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Registry Numbers
MDL Number
MFCD01075684
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Storage & Handling
Storage
Room temperature, dry, sealed
description Product Description
Used as a key intermediate in the synthesis of angiotensin II receptor antagonists, particularly in the production of sartan-class antihypertensive drugs such as valsartan and losartan. Its structure enables effective binding to the angiotensin II receptor, helping regulate blood pressure. The compound’s tetrazole ring serves as a bioisostere for the carboxylic acid group, improving metabolic stability and oral bioavailability in pharmaceutical formulations. It is widely utilized in medicinal chemistry for developing cardiovascular therapeutics.
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