3-Cyano-3'-hydroxybiphenyl
98%
Reagent
Code: #166635
CAS Number
154848-43-8
blur_circular Chemical Specifications
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Molecular Information
Weight
195.22 g/mol
Formula
C₁₃H₉NO
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Registry Numbers
MDL Number
MFCD05854256
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Storage & Handling
Storage
Room temperature
description Product Description
Used as a key intermediate in the synthesis of angiotensin II receptor antagonists, particularly in the production of antihypertensive drugs like valsartan and related pharmaceuticals. Its structure allows for the formation of biaryl motifs commonly found in sartan-class medications, which are widely prescribed for the treatment of high blood pressure and heart failure. The cyano and hydroxyl functional groups provide reactive sites for further chemical modifications during drug manufacturing. It is valued in medicinal chemistry for its ability to enhance binding affinity and selectivity in the final active pharmaceutical ingredient.
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