5-(4-Chlorophenyl)-1H-tetrazole
≥97%
Reagent
Code: #173762
CAS Number
16687-61-9
blur_circular Chemical Specifications
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Molecular Information
Weight
180.59 g/mol
Formula
C₇H₅ClN₄
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Registry Numbers
MDL Number
MFCD00040952
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Storage & Handling
Storage
2-8°C
description Product Description
Used as a key intermediate in the synthesis of angiotensin II receptor antagonists, particularly in the production of sartan-class antihypertensive drugs such as valsartan and losartan. Its tetrazole ring serves as a bioisostere for the carboxylic acid group, enhancing metabolic stability and improving pharmacokinetic properties. Also employed in coordination chemistry as a ligand for metal ions due to its nitrogen-rich structure. Additionally, finds use in materials science for developing energetic materials and corrosion inhibitors.
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