2-Methoxy-4-(1H-tetrazol-5-yl)phenol
≥95%
Reagent
Code: #173766
CAS Number
376609-66-4
blur_circular Chemical Specifications
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Molecular Information
Weight
192.17 g/mol
Formula
C₈H₈N₄O₂
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Registry Numbers
MDL Number
MFCD17430401
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Storage & Handling
Storage
2-8°C
description Product Description
Used in pharmaceutical synthesis as a key intermediate for angiotensin II receptor antagonists, particularly in the production of sartan-class drugs like losartan and candesartan. Its tetrazole moiety mimics the carboxylic acid group in bioactive molecules, enhancing binding affinity to the angiotensin II receptor. Also employed in research for developing new antihypertensive agents due to its metabolic stability and favorable pharmacokinetic properties.
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