5-(4-Bromo-2-fluorophenyl)-2H-tetrazole
95%
Reagent
Code: #173768
CAS Number
530081-35-7
blur_circular Chemical Specifications
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Molecular Information
Weight
243.04 g/mol
Formula
C₇H₄BrFN₄
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Registry Numbers
MDL Number
MFCD04035676
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Storage & Handling
Storage
2-8°C
description Product Description
Used as a key intermediate in the synthesis of angiotensin II receptor antagonists, particularly in the production of antihypertensive drugs like valsartan and related sartan-class medications. Its structure enables effective binding to the angiotensin II receptor, helping to block vasoconstriction and regulate blood pressure. Widely utilized in pharmaceutical research and development for designing potent and selective cardiovascular therapeutics. Also employed in the preparation of other bioactive molecules due to its stable tetrazole ring, which can act as a bioisostere for carboxylic acid groups, improving metabolic stability and oral bioavailability in drug candidates.
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