3-(2H-Tetrazol-5-yl)benzonitrile
≥95%
Reagent
Code: #173773
CAS Number
50907-33-0
blur_circular Chemical Specifications
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Molecular Information
Weight
171.16 g/mol
Formula
C₈H₅N₅
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Registry Numbers
MDL Number
MFCD06797249
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Storage & Handling
Storage
2-8°C
description Product Description
Used as a key intermediate in the synthesis of angiotensin II receptor antagonists, particularly in the production of sartan-class antihypertensive drugs like candesartan and valsartan. Its tetrazole ring mimics the carboxylic acid group in biological systems, enhancing binding affinity to the angiotensin II receptor. Widely employed in pharmaceutical research and development for cardiovascular medications. Also utilized in the preparation of other bioactive molecules where tetrazole functionality is required for activity.
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