Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the production of angiotensin II receptor antagonists like losartan and related drugs for treating hypertension. Its strong acidic character makes it valuable in coordination chemistry and as a ligand in catalysis. Also employed in agrochemicals to enhance metabolic stability and bioavailability due to the trifluoromethyl group. Additionally, finds use in materials science for developing energetic compounds and high-performance polymers with improved thermal and oxidative stability.