Docosenylsuccinic anhydride (DSA) is primarily utilized as an internal sizing agent in the paper industry, where it reacts with cellulose fibers to impart water repellency, improve surface strength, and enhance printability of paper and board products.

It also functions as a reactive intermediate and curing agent in epoxy resin formulations, enhancing mechanical strength, thermal stability, and adhesion in coatings, adhesives, and composite materials.

Additionally, DSA is employed in the synthesis of specialty surfactants, ashless dispersants for lubricants, and corrosion inhibitors, owing to its amphiphilic structure that modifies surface properties, reduces friction, and provides dispersancy in industrial applications.