Emulgel™ Baicalin is an emulsion‑gel concentrate of baicalin designed to maximize topical delivery and skin tolerance in high‑performance skincare. The emulgel matrix combines an aqueous gel network with a small oil fraction to aid deposition and sensorial feel.
Baicalin (from Scutellaria baicalensis) is a flavone with antioxidant and anti‑inflammatory activity relevant to photoaging defense and recovery. In keratinocyte models it reduces UV‑induced ROS, limits DNA photolesions (e.g., CPDs, 8‑oxo‑dG), and down‑modulates TLR4‑mediated signaling while engaging cytoprotective programs (e.g., HO‑1/Nrf2). The emulgel format improves apparent solubilization and cutaneous uptake versus dry powders. This concentrate contains approximately ~6.7% baicalin active.
Product Description: Cyclodextrin‑assisted emulsion‑gel system pre‑loaded with baicalin to facilitate incorporation into water‑based and emulsion formulations without specialized milling.
| Model/System |
Key Endpoints |
Implication |
| Keratinocytes (UV) |
↓ ROS; ↓ CPDs/8‑oxo‑dG; ↓ TLR4; ↑ HO‑1/Nrf2 |
Photoaging moderation; post‑UV recovery |
| Human combo serum |
Texture/lines/laxity/tone/radiance improved (12 weeks) |
Visible anti‑aging (blend) |
| Psoriasis mouse |
↓ inflammatory readouts; lesion scores improved |
Calming/anti‑redness support |
| Wound model |
Faster closure; better granulation/maturation |
Supportive for minor wounds |
| Hair cycle (mice) |
↑ Wnt/β‑catenin; anagen promotion |
Scalp‑care concept (preclinical) |
Usage: Day and night facial care (serums, lotions, creams), after‑sun recovery, soothing/anti‑redness moisturizers, eye‑area products (evaluate color/transfer), scalp leave‑on tonics.
Mixing method:
- Add during cool‑down (≤40°C) with moderate shear until homogeneous. Compatible with the water phase or the continuous phase of O/W emulsions.
- Target finished pH ~5.0–6.5; avoid highly alkaline or strongly acidic endpoints. Verify color/clarity in transparent systems and adjust solubilizers as needed.
- Avoid strong oxidizers and prolonged high heat. In very low‑viscosity bases, a small amount of polymeric thickener can help maintain uniform dispersion.
Usage rate: 0.74–2.97% (of this ingredient) — delivers ~0.05–0.20% baicalin active in the finished formula. Typical working level: ~1.85%.
Product characteristics: Light yellow gel/gel‑cream concentrate with mild characteristic odor.
Solubility: Water‑dispersible emulgel; readily disperses into water and O/W emulsions. Apparent solubilization of baicalin is aided by the matrix; transparency depends on base and level.
Storage: Keep tightly closed in a cool, dry place away from light (15–25°C). Do not freeze. Typical shelf life 24 months under proper storage.
