Cimicifugoside is primarily used in pharmaceutical and nutraceutical research due to its bioactive properties. It exhibits anti-inflammatory and neuroprotective effects, making it a compound of interest in the development of treatments for neurodegenerative conditions such as Alzheimer's and Parkinson’s disease. Studies suggest it may help modulate oxidative stress and reduce neuronal damage by influencing signaling pathways related to cell survival. It is also investigated for its potential in managing menopausal symptoms, owing to its presence in plant extracts traditionally used for hormonal balance. Its ability to interact with serotonin receptors and influence mood-related pathways supports its use in natural remedies for anxiety and depression. In addition, cimicifugoside shows mild antioxidant activity, which contributes to its inclusion in formulations aimed at cellular protection and anti-aging. Due to these diverse biological activities, it serves as a lead compound in drug discovery and is used in standardized herbal extracts for quality control and efficacy assessment.